• Diagnostic Solutions Laboratory Zonulin Stool test
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Zonulin Stool Test

Zonulin Stool Test

The zonulin marker assesses for hyperpermeability in the gut lining. The lining of the gut is composed of a single layer of cells that are held together by something called tight junctions. These tight junctions are meant to be able to open and close based upon the needs of the system at any particular time. Zonulin regulates the opening of the tight junctions. While this is desirable at times, certain types of infections and gliadin (the oft-problematic protein in gluten) can upregulate zonulin and create chronic intestinal hyperpermeability (aka leaky gut).t

Zonulin may also be suggestive of a leaky brain beyond just a leaky gut.

$149.00
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*This test is only available in the U.S., excluding New York.
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Frequently Asked Questions

Who is this for?

This test can be run for men or women, and there is no upper age limit to run this test. This test is a great idea for anyone struggling with:

  • Autoimmune diseases
  • IBS/IBD
  • Digestive complaints, diarrhea or constipation
  • Skin problems, like acne and psoriasis
  • Mood disorders, depression, and anxiety
  • Diabetes and weight loss issues
  • Hormonal Imbalances
  • Thyroid dysfunction

What is the timeframe?

Once you place your order, we will ship your test kit to you. Once you run your test, expect about 2-3 weeks before the results are back and you review your 30-minute interpretation and plan

What Is the zonulin optional addition?

The zonulin marker assesses for hyperpermeability in the gut lining. The lining of the gut is composed of a single layer of cells that are held together by something called tight junctions. These tight junctions are meant to be able to open and close based upon the needs of the system at any particular time. Zonulin regulates the opening of the tight junctions. While this is desirable at times, certain types of infections and gliadin (the oft-problematic protein in gluten) can upregulate zonulin and create chronic intestinal hyperpermeability (aka leaky gut).

While the GI Map does test for the anti-gliadin antibody (associated with non-celiac gluten sensitivity) this part of the test can sometimes return negative even if leaky gut is present. The zonulin add-on is useful to see if grains could be causing a leaky gut.

Zonulin may also be suggestive of a leaky brain beyond just a leaky gut. Dr. Michelle believes this is a really great marker.

What are the preparation instructions?

Please click here to see the preparation and shipping instructions from the lab.

Do you take insurance?

We do not bill insurance or provide you with specific documents to submit to your insurance. We do provide you with a transaction receipt, but these receipts are not recognized by many insurance companies. However, if you have a Health Savings Account (HSA) credit card, you should be able to purchase this service on that card. If you have trouble getting your HSA card to work on our site, we can send an invoice instead. Simply email us at support@glownaturalwellness.com.